

In [1]:

    
import os
import libsbml
from pprint import pprint

from sbmlutils import comp
from sbmlutils import validation
from sbmlutils import manipulation
from sbmlutils.tests.data import data_dir

merge_dir = os.path.join(data_dir, 'manipulation', 'merge')

# dictionary of ids & paths of models which should be combined
# here we just bring together the first Biomodels
model_ids = ["BIOMD000000000{}".format(k) for k in range(1, 5)]
model_paths = dict(zip(model_ids,
                       [os.path.join(merge_dir, "{}.xml".format(mid)) for mid in model_ids])
                   )
pprint(model_paths)

# create merged model
output_dir = os.path.join(merge_dir, 'output')
doc = manipulation.merge_models(model_paths, out_dir=output_dir, validate=False)

# validate
Nall, Nerr, Nwarn = validation.check_doc(doc, units_consistency=False)
assert Nerr == 0
assert Nwarn == 0
assert Nall == 0

# write the merged model
print(libsbml.writeSBMLToString(doc))
libsbml.writeSBMLToFile(doc, os.path.join(output_dir, "merged.xml"))

# flatten the merged model
doc_flat = comp.flattenSBMLDocument(doc)
Nall, Nerr, Nwarn = validation.check_doc(doc_flat, units_consistency=False)
libsbml.writeSBMLToFile(doc_flat, os.path.join(output_dir, "merged_flat.xml"));









    



{'BIOMD0000000001': '/home/mkoenig/git/sbmlutils/sbmlutils/tests/data/manipulation/merge/BIOMD0000000001.xml',
 'BIOMD0000000002': '/home/mkoenig/git/sbmlutils/sbmlutils/tests/data/manipulation/merge/BIOMD0000000002.xml',
 'BIOMD0000000003': '/home/mkoenig/git/sbmlutils/sbmlutils/tests/data/manipulation/merge/BIOMD0000000003.xml',
 'BIOMD0000000004': '/home/mkoenig/git/sbmlutils/sbmlutils/tests/data/manipulation/merge/BIOMD0000000004.xml'}

--------------------------------------------------------------------------------
<SBMLDocument>
valid                    : TRUE
check time (s)           : 0.032
--------------------------------------------------------------------------------

<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level3/version1/core" xmlns:comp="http://www.sbml.org/sbml/level3/version1/comp/version1" level="3" version="1" comp:required="true">
  <model id="merged">
    <comp:listOfSubmodels>
      <comp:submodel comp:id="BIOMD0000000001" comp:modelRef="BIOMD0000000001"/>
      <comp:submodel comp:id="BIOMD0000000002" comp:modelRef="BIOMD0000000002"/>
      <comp:submodel comp:id="BIOMD0000000003" comp:modelRef="BIOMD0000000003"/>
      <comp:submodel comp:id="BIOMD0000000004" comp:modelRef="BIOMD0000000004"/>
    </comp:listOfSubmodels>
  </model>
  <comp:listOfExternalModelDefinitions>
    <comp:externalModelDefinition comp:id="BIOMD0000000001" comp:name="BIOMD0000000001" comp:source="/home/mkoenig/git/sbmlutils/sbmlutils/tests/data/manipulation/merge/output/BIOMD0000000001_L3.xml" comp:modelRef="BIOMD0000000001"/>
    <comp:externalModelDefinition comp:id="BIOMD0000000002" comp:name="BIOMD0000000002" comp:source="/home/mkoenig/git/sbmlutils/sbmlutils/tests/data/manipulation/merge/output/BIOMD0000000002_L3.xml" comp:modelRef="BIOMD0000000002"/>
    <comp:externalModelDefinition comp:id="BIOMD0000000003" comp:name="BIOMD0000000003" comp:source="/home/mkoenig/git/sbmlutils/sbmlutils/tests/data/manipulation/merge/output/BIOMD0000000003_L3.xml" comp:modelRef="BIOMD0000000003"/>
    <comp:externalModelDefinition comp:id="BIOMD0000000004" comp:name="BIOMD0000000004" comp:source="/home/mkoenig/git/sbmlutils/sbmlutils/tests/data/manipulation/merge/output/BIOMD0000000004_L3.xml" comp:modelRef="BIOMD0000000004"/>
  </comp:listOfExternalModelDefinitions>
</sbml>


--------------------------------------------------------------------------------
<SBMLDocument>
valid                    : TRUE
check time (s)           : 0.028
--------------------------------------------------------------------------------

SBML manipulation

Model merging