Scenario 1 : random mating for 10 generations for one population
reading real genotypes from files
In [5]:
%%file main.cpp
#include <iostream>
#include <fstream>
#include "cohort.h"
#include "tools.h"
#include "simPop.h"
#include "global.h"
#include "parmMap.h"
int main(int argc, const char * argv[])
{
///user-defined parameters and map positions
unsigned popSize = 10;
unsigned nGen = 10;
string path="/Users/erxingfangshui/Dropbox/GenSim/GenSim1.4/data/";
string genomeFile=path+"genomeInfo.txt";
string mapFile=path+"mapPos.txt";
string haplotype=path+"haplotype.txt";
SimPop osim(genomeFile,mapFile);
osim.popFounders(popSize,haplotype);
osim.popSample(popSize,nGen);
MatrixXf out;
out=osim.getGenotypes();
ofstream outFile(path+"genotype.txt");
outFile << out;
return 0;
}
randomly generate genotypes
In [ ]:
%%file main.cpp
#include <iostream>
#include <fstream>
#include "cohort.h"
#include "tools.h"
#include "simPop.h"
#include "global.h"
#include "parmMap.h"
int main(int argc, const char * argv[])
{
///constant nLoci, chrLength and random map positions
unsigned nLoci = 100;
unsigned nChrm = 1;
double chrLength = 0.01;
unsigned popSize = 100;
unsigned nGen = 10;
double mutRate = 1e-5;
SimPop osim(nChrm,nLoci,chrLength,mutRate);
osim.popFounders(popSize);
osim.popSample(popSize,nGen);
MatrixXf out;
out=osim.getGenotypes();
ofstream outFile("genotype.example");
outFile << out;
cout<<"DONE"<<endl;
return 0;
}
In [2]:
%%file makeGenSim
#############################################################################
# Makefile for building: OSim
myPath = /Users/erxingfangshui/Dropbox/CODE
INCPATH = -I $(myPath)/eigen3 -I $(myPath)/boost
GenSim: main.o libGenSim.a
g++ -o GenSim main.o libGenSim.a
main.o: main.cpp
g++ $(INCPATH) -c -o main.o main.cpp
clean:
\rm main.o GenSim
In [2]:
%%bash
path=/Users/erxingfangshui/Dropbox/GenSim/GenSim1.4
mv makeGenSim $path
mv main.cpp $path
cd $path
make -f makeGenSim
In [3]:
%%bash
path=/Users/erxingfangshui/Dropbox/GenSim/GenSim1.4
cd $path
./GenSim