In [1]:
from biothings_explorer.hint import Hint
from biothings_explorer.user_query_dispatcher import FindConnection
In [2]:
ht = Hint()
ace2 = ht.query("ACE2")['Gene'][0]
ace2
Out[2]:
{'NCBIGene': '59272',
'name': 'angiotensin I converting enzyme 2',
'SYMBOL': 'ACE2',
'UMLS': 'C1422064',
'HGNC': '13557',
'UNIPROTKB': 'Q9BYF1',
'ENSEMBL': 'ENSG00000130234',
'primary': {'identifier': 'NCBIGene', 'cls': 'Gene', 'value': '59272'},
'display': 'NCBIGene(59272) ENSEMBL(ENSG00000130234) HGNC(13557) UMLS(C1422064) UNIPROTKB(Q9BYF1) SYMBOL(ACE2)',
'type': 'Gene'}
In [5]:
fc = FindConnection(input_obj=ace2,
output_obj='Disease',
intermediate_nodes=None)
In [6]:
fc.connect(verbose=True)
==========
========== QUERY PARAMETER SUMMARY ==========
==========
BTE will find paths that join 'ACE2' and 'Disease'. Paths will have 0 intermediate node.
========== QUERY #1 -- fetch all Disease entities linked to ACE2 ==========
==========
==== Step #1: Query path planning ====
Because ACE2 is of type 'Gene', BTE will query our meta-KG for APIs that can take 'Gene' as input and 'Disease' as output
BTE found 10 apis:
API 1. cord_gene(1 API call)
API 2. semmed_gene(13 API calls)
API 3. biolink(1 API call)
API 4. scibite(1 API call)
API 5. ctd(1 API call)
API 6. DISEASES(1 API call)
API 7. mydisease(1 API call)
API 8. pharos(1 API call)
API 9. hetio(1 API call)
API 10. scigraph(1 API call)
==== Step #2: Query path execution ====
NOTE: API requests are dispatched in parallel, so the list of APIs below is ordered by query time.
API 7.1: http://mydisease.info/v1/query?fields=disgenet.xrefs.umls&size=250 (POST -d q=59272&scopes=disgenet.genes_related_to_disease.gene_id)
API 3.4: https://biothings.ncats.io/semmedgene/query?fields=disrupted_by (POST -d q=C1422064&scopes=umls)
API 3.11: https://biothings.ncats.io/semmedgene/query?fields=affected_by (POST -d q=C1422064&scopes=umls)
API 3.3: https://biothings.ncats.io/semmedgene/query?fields=physically_interacts_with (POST -d q=C1422064&scopes=umls)
API 3.7: https://biothings.ncats.io/semmedgene/query?fields=positively_regulated_by (POST -d q=C1422064&scopes=umls)
API 3.9: https://biothings.ncats.io/semmedgene/query?fields=treats (POST -d q=C1422064&scopes=umls)
API 3.10: https://biothings.ncats.io/semmedgene/query?fields=related_to (POST -d q=C1422064&scopes=umls)
API 2.1: https://api.monarchinitiative.org/api/bioentity/gene/NCBIGene:59272/diseases?rows=200
API 3.2: https://biothings.ncats.io/semmedgene/query?fields=disrupts (POST -d q=C1422064&scopes=umls)
API 3.1: https://biothings.ncats.io/semmedgene/query?fields=positively_regulates (POST -d q=C1422064&scopes=umls)
API 3.12: https://biothings.ncats.io/semmedgene/query?fields=negatively_regulates (POST -d q=C1422064&scopes=umls)
API 3.5: https://biothings.ncats.io/semmedgene/query?fields=negatively_regulated_by (POST -d q=C1422064&scopes=umls)
API 3.6: https://biothings.ncats.io/semmedgene/query?fields=causes (POST -d q=C1422064&scopes=umls)
API 3.8: https://biothings.ncats.io/semmedgene/query?fields=prevents (POST -d q=C1422064&scopes=umls)
API 3.13: https://biothings.ncats.io/semmedgene/query?fields=affects (POST -d q=C1422064&scopes=umls)
API 5.1: http://ctdbase.org/tools/batchQuery.go?inputType=gene&report=diseases_curated&format=json&inputTerms=59272
API 6.1: https://pending.biothings.io/DISEASES/query?fields=DISEASES.doid&size=250 (POST -d q=ACE2&scopes=DISEASES.associatedWith.symbol)
API 1.1: https://biothings.ncats.io/cord_gene/query?fields=associated_with (POST -d q=13557&scopes=hgnc)
API 8.1: https://automat.renci.org/pharos/gene/disease/NCBIGene:59272
API 9.1: https://automat.renci.org/hetio/gene/disease/NCBIGene:59272
API 10.1: https://automat.renci.org/cord19_scigraph_v2/gene/disease/NCBIGene:59272
API 4.1: https://automat.renci.org/cord19_scibite_v2/gene/disease/NCBIGene:59272
==== Step #3: Output normalization ====
API 3.1 semmed_gene: No hits
API 3.2 semmed_gene: 8 hits
API 3.3 semmed_gene: No hits
API 4.1 scibite: 44 hits
API 3.4 semmed_gene: No hits
API 6.1 DISEASES: 31 hits
API 3.5 semmed_gene: No hits
API 3.6 semmed_gene: 17 hits
API 3.7 semmed_gene: No hits
API 8.1 pharos: 4 hits
API 9.1 hetio: 5 hits
API 2.1 biolink: No hits
API 7.1 mydisease: 7 hits
API 3.8 semmed_gene: 6 hits
API 3.9 semmed_gene: 12 hits
API 10.1 scigraph: 41 hits
API 3.10 semmed_gene: 57 hits
API 3.11 semmed_gene: No hits
API 1.1 cord_gene: 4 hits
API 3.12 semmed_gene: No hits
API 3.13 semmed_gene: 17 hits
API 5.1 ctd: 17 hits
After id-to-object translation, BTE retrieved 156 unique objects.
==========
========== Final assembly of results ==========
==========
In the #1 query, BTE found 156 unique Disease nodes
In [7]:
fc.to_reasoner_std()
Out[7]:
{'query_graph': {'edges': [{'id': 'e0',
'source_id': 'n0',
'target_id': 'n1',
'directed': True}],
'nodes': [{'id': 'n0', 'type': 'Gene', 'curie': ['NCBIGene:59272']},
{'id': 'n1', 'type': 'Disease'}]},
'knowledge_graph': {'nodes': [{'id': 'SYMBOL:ACE2',
'name': 'ANGIOTENSIN I CONVERTING ENZYME 2',
'type': 'Gene',
'equivalent_identifiers': defaultdict(set,
{'NCBIGene': ['59272'],
'name': ['ANGIOTENSIN I CONVERTING ENZYME 2'],
'SYMBOL': ['ACE2'],
'UMLS': ['C1422064'],
'HGNC': ['13557'],
'UNIPROTKB': ['Q9BYF1'],
'ENSEMBL': ['ENSG00000130234']})},
{'id': 'UMLS:C0221198',
'name': 'UMLS:C0221198',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0221198']}},
{'id': 'UMLS:C0262613',
'name': 'UMLS:C0262613',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0262613']}},
{'id': 'UMLS:C0264716',
'name': 'UMLS:C0264716',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0264716']}},
{'id': 'UMLS:C1397014',
'name': 'UMLS:C1397014',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C1397014']}},
{'id': 'UMLS:C0009566',
'name': 'UMLS:C0009566',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0009566']}},
{'id': 'UMLS:C0011847',
'name': 'UMLS:C0011847',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0011847']}},
{'id': 'UMLS:C0015697',
'name': 'UMLS:C0015697',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0015697']}},
{'id': 'UMLS:C0242606',
'name': 'UMLS:C0242606',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0242606']}},
{'id': 'UMLS:C0332448',
'name': 'UMLS:C0332448',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0332448']}},
{'id': 'UMLS:C0340515',
'name': 'UMLS:C0340515',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0340515']}},
{'id': 'UMLS:C0522569',
'name': 'UMLS:C0522569',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0522569']}},
{'id': 'UMLS:C1291117',
'name': 'UMLS:C1291117',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C1291117']}},
{'id': 'UMLS:C0277785',
'name': 'UMLS:C0277785',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0277785']}},
{'id': 'UMLS:C0699748',
'name': 'UMLS:C0699748',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0699748']}},
{'id': 'UMLS:C1155266',
'name': 'UMLS:C1155266',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C1155266']}},
{'id': 'UMLS:C0231176',
'name': 'UMLS:C0231176',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0231176']}},
{'id': 'UMLS:C1301752',
'name': 'UMLS:C1301752',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C1301752']}},
{'id': 'UMLS:C0030660',
'name': 'UMLS:C0030660',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0030660']}},
{'id': 'UMLS:C0087086',
'name': 'UMLS:C0087086',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0087086']}},
{'id': 'UMLS:C0149939',
'name': 'UMLS:C0149939',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0149939']}},
{'id': 'UMLS:C0520863',
'name': 'UMLS:C0520863',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0520863']}},
{'id': 'UMLS:C0878751',
'name': 'UMLS:C0878751',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0878751']}},
{'id': 'UMLS:C0920563',
'name': 'UMLS:C0920563',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0920563']}},
{'id': 'UMLS:C1301700',
'name': 'UMLS:C1301700',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C1301700']}},
{'id': 'UMLS:C0879626',
'name': 'UMLS:C0879626',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0879626']}},
{'id': 'UMLS:C0160420',
'name': 'UMLS:C0160420',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0160420']}},
{'id': 'UMLS:C0518003',
'name': 'UMLS:C0518003',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0518003']}},
{'id': 'UMLS:C0684309',
'name': 'UMLS:C0684309',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0684309']}},
{'id': 'UMLS:C0687133',
'name': 'UMLS:C0687133',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C0687133']}},
{'id': 'UMLS:C1446614',
'name': 'UMLS:C1446614',
'type': 'Disease',
'equivalent_identifiers': {'UMLS': ['C1446614']}},
{'id': 'MONDO:MONDO:0100096',
'name': 'MONDO:MONDO:0100096',
'type': 'Disease',
'equivalent_identifiers': {'MONDO': ['MONDO:0100096']}},
{'id': 'MESH:D000022',
'name': 'MESH:D000022',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MESH:D000022'], 'MESH': ['D000022']})},
{'id': 'MESH:C000657245',
'name': 'MESH:C000657245',
'type': 'Disease',
'equivalent_identifiers': {'MESH': ['C000657245']}},
{'id': 'MESH:D007249',
'name': 'MESH:D007249',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MESH:D007249'], 'MESH': ['D007249']})},
{'id': 'MESH:D055370',
'name': 'MESH:D055370',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MESH:D055370'], 'MESH': ['D055370']})},
{'id': 'DOID:DOID:162',
'name': 'DOID:DOID:162',
'type': 'Disease',
'equivalent_identifiers': {'DOID': ['DOID:162']}},
{'id': 'DOID:DOID:0080600',
'name': 'DOID:DOID:0080600',
'type': 'Disease',
'equivalent_identifiers': {'DOID': ['DOID:0080600']}},
{'id': 'NAME:INFLAMMATION',
'name': 'INFLAMMATION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0021368'],
'UMLS': ['C0021368'],
'name': ['INFLAMMATION']})},
{'id': 'NAME:PULMONARY FIBROSIS',
'name': 'PULMONARY FIBROSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0002771'],
'DOID': ['DOID:3770'],
'UMLS': ['C0034069'],
'name': ['PULMONARY FIBROSIS'],
'MESH': ['D011658']})},
{'id': 'NAME:MYOCARDIAL FIBROSIS',
'name': 'MYOCARDIAL FIBROSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0151654'],
'UMLS': ['C0151654'],
'name': ['MYOCARDIAL FIBROSIS']})},
{'id': 'NAME:AAA1',
'name': 'AAA1',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0007031', 'MONDO:0024521'],
'UMLS': ['C0162871', 'C1853365'],
'name': ['AAA1',
'AORTIC ANEURYSM, ABDOMINAL',
'AORTIC ANEURYSM, FAMILIAL ABDOMINAL 1',
'FAMILIAL ABDOMINAL AORTIC ANEURYSM'],
'ORPHANET': ['86'],
'OMIM': ['100070']})},
{'id': 'NAME:CARDIOVASCULAR DISEASE',
'name': 'CARDIOVASCULAR DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0004995'],
'DOID': ['DOID:1287'],
'UMLS': ['C0007222'],
'name': ['CARDIOVASCULAR DISEASE', 'CARDIOVASCULAR DISEASES'],
'MESH': ['D002318']})},
{'id': 'NAME:FIBROSIS',
'name': 'FIBROSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0016059'],
'UMLS': ['C0016059'],
'name': ['FIBROSIS']})},
{'id': 'NAME:CONGENITAL HEART DEFECTS',
'name': 'CONGENITAL HEART DEFECTS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005453'],
'DOID': ['DOID:1682'],
'UMLS': ['C0152021', 'C0018798'],
'name': ['CONGENITAL HEART DEFECTS',
'CONGENITAL HEART DISEASE'],
'MESH': ['D006330']})},
{'id': 'NAME:HYPERGLYCEMIA',
'name': 'HYPERGLYCEMIA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0002909'],
'DOID': ['DOID:4195'],
'UMLS': ['C0020456'],
'name': ['HYPERGLYCEMIA'],
'MESH': ['D006943']})},
{'id': 'NAME:WEIGHT GAIN',
'name': 'WEIGHT GAIN',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0043094'],
'UMLS': ['C0043094'],
'name': ['WEIGHT GAIN']})},
{'id': 'NAME:GLOMERULOSCLEROSIS',
'name': 'GLOMERULOSCLEROSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0000490'],
'DOID': ['DOID:0050851'],
'UMLS': ['C0178664'],
'name': ['GLOMERULOSCLEROSIS',
'GLOMERULOSCLEROSIS (DISORDER)']})},
{'id': 'NAME:ACUTE LUNG INJURY',
'name': 'ACUTE LUNG INJURY',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0015796'],
'UMLS': ['C0242488'],
'name': ['ACUTE LUNG INJURY'],
'MESH': ['D055371'],
'ORPHANET': ['178320']})},
{'id': 'NAME:ACUTE RESPIRATORY CORONAVIRUS INFECTION',
'name': 'ACUTE RESPIRATORY CORONAVIRUS INFECTION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0015370', 'MONDO:0005091'],
'DOID': ['DOID:2945'],
'UMLS': ['C1175175'],
'name': ['ACUTE RESPIRATORY CORONAVIRUS INFECTION',
'SEVERE ACUTE RESPIRATORY SYNDROME'],
'MESH': ['D045169'],
'ORPHANET': ['140896']})},
{'id': 'NAME:INSULIN RESISTANCE',
'name': 'INSULIN RESISTANCE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0021655'],
'UMLS': ['C0021655'],
'name': ['INSULIN RESISTANCE']})},
{'id': 'NAME:MALIGNANT SQUAMOUS CELL NEOPLASM',
'name': 'MALIGNANT SQUAMOUS CELL NEOPLASM',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005096', 'MONDO:0000500'],
'DOID': ['DOID:1749', 'DOID:0050865'],
'UMLS': ['C0751688', 'C0007137'],
'name': ['MALIGNANT SQUAMOUS CELL NEOPLASM',
'SQUAMOUS CELL CARCINOMA',
'TONGUE SQUAMOUS CELL CARCINOMA'],
'MESH': ['D018307', 'D002294']})},
{'id': 'NAME:DISEASE',
'name': 'DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0000001'],
'DOID': ['DOID:4'],
'UMLS': ['C0012634'],
'name': ['DISEASE'],
'MESH': ['D004194'],
'ORPHANET': ['377788']})},
{'id': 'NAME:DYSAUTONOMIA',
'name': 'DYSAUTONOMIA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0013363'],
'UMLS': ['C0013363'],
'name': ['DYSAUTONOMIA']})},
{'id': 'NAME:CONGESTIVE HEART FAILURE',
'name': 'CONGESTIVE HEART FAILURE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005009', 'MONDO:0005252'],
'UMLS': ['C0018801', 'C0018802'],
'name': ['CONGESTIVE HEART FAILURE', 'HEART FAILURE'],
'MESH': ['D006333'],
'DOID': ['DOID:6000']})},
{'id': 'NAME:RIGHT VENTRICULAR HYPERTROPHY',
'name': 'RIGHT VENTRICULAR HYPERTROPHY',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0162770'],
'UMLS': ['C0162770'],
'name': ['RIGHT VENTRICULAR HYPERTROPHY']})},
{'id': 'NAME:GLOMERULAR DISEASE',
'name': 'GLOMERULAR DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0019722'],
'UMLS': ['C0268731'],
'name': ['GLOMERULAR DISEASE', 'RENAL GLOMERULAR DISEASE'],
'ORPHANET': ['93548']})},
{'id': 'NAME:ADENOCARCINOMA',
'name': 'ADENOCARCINOMA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0004970'],
'DOID': ['DOID:299'],
'UMLS': ['C0001418'],
'name': ['ADENOCARCINOMA'],
'MESH': ['D000230']})},
{'id': 'NAME:ALZHEIMER DISEASE TYPE 1',
'name': 'ALZHEIMER DISEASE TYPE 1',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0007088', 'MONDO:0004975'],
'DOID': ['DOID:10652'],
'UMLS': ['C0002395', 'C1863052'],
'name': ['ALZHEIMER DISEASE TYPE 1',
'ALZHEIMER DISEASE, FAMILIAL, 1',
"ALZHEIMER'S DISEASE",
'ALZHEIMERS DISEASE'],
'MESH': ['D000544'],
'OMIM': ['104300']})},
{'id': 'NAME:ARTERIOSCLEROTIC CARDIOVASCULAR DISEASE',
'name': 'ARTERIOSCLEROTIC CARDIOVASCULAR DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0002276', 'MONDO:0005311'],
'DOID': ['DOID:2348', 'DOID:1936'],
'UMLS': ['C3665365', 'C0004153'],
'name': ['ARTERIOSCLEROTIC CARDIOVASCULAR DISEASE',
'ARTERIOSCLEROTIC CARDIOVASCULAR DISEASE, NOS',
'ATHEROSCLEROSIS'],
'MESH': ['D050197']})},
{'id': 'NAME:ATRIAL FIBRILLATION',
'name': 'ATRIAL FIBRILLATION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0004981'],
'DOID': ['DOID:0060224'],
'UMLS': ['C0004238'],
'name': ['ATRIAL FIBRILLATION',
'ATRIAL FIBRILLATION (DISEASE)'],
'MESH': ['D001281']})},
{'id': 'NAME:HEREDITARY PAPILLARY RENAL CARCINOMA',
'name': 'HEREDITARY PAPILLARY RENAL CARCINOMA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005086', 'MONDO:0005549', 'MONDO:0017884'],
'UMLS': ['C0007134',
'C2931899',
'C1306837',
'C1336839',
'C0879257'],
'name': ['HEREDITARY PAPILLARY RENAL CARCINOMA',
'PAPILLARY RENAL CELL CARCINOMA',
'PAPILLARY RENAL CELL CARCINOMA, FAMILIAL',
'RENAL CELL ADENOCARCINOMA',
'RENAL CELL CARCINOMA',
'RENAL CELL CARCINOMA (DISEASE)',
'TYPE 1 PAPILLARY RENAL CELL CARCINOMA'],
'DOID': ['DOID:4465', 'DOID:4450'],
'MESH': ['D002292'],
'ORPHANET': ['217071', '319298'],
'OMIM': ['605074']})},
{'id': 'NAME:CARDIOMYOPATHY, DILATED',
'name': 'CARDIOMYOPATHY, DILATED',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005021'],
'DOID': ['DOID:12930'],
'UMLS': ['C0007193'],
'name': ['CARDIOMYOPATHY, DILATED', 'DILATED CARDIOMYOPATHY'],
'MESH': ['D002311'],
'ORPHANET': ['217604']})},
{'id': 'NAME:DIABETES MELLITUS, INSULIN-DEPENDENT',
'name': 'DIABETES MELLITUS, INSULIN-DEPENDENT',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005147'],
'DOID': ['DOID:9744'],
'UMLS': ['C0011854'],
'name': ['DIABETES MELLITUS, INSULIN-DEPENDENT',
'TYPE 1 DIABETES MELLITUS'],
'MESH': ['D003922']})},
{'id': 'NAME:DIABETES MELLITUS',
'name': 'DIABETES MELLITUS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005015'],
'DOID': ['DOID:9351'],
'UMLS': ['C0011849'],
'name': ['DIABETES MELLITUS', 'DIABETES MELLITUS (DISEASE)'],
'MESH': ['D003920']})},
{'id': 'NAME:DIABETIC NEPHROPATHY',
'name': 'DIABETIC NEPHROPATHY',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005016'],
'UMLS': ['C0011881'],
'name': ['DIABETIC NEPHROPATHY'],
'MESH': ['D003928']})},
{'id': 'NAME:IGA GLOMERULONEPHRITIS',
'name': 'IGA GLOMERULONEPHRITIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005342'],
'DOID': ['DOID:2986'],
'UMLS': ['C0017661'],
'name': ['IGA GLOMERULONEPHRITIS'],
'MESH': ['D005922']})},
{'id': 'NAME:MEMBRANOUS GLOMERULONEPHRITIS',
'name': 'MEMBRANOUS GLOMERULONEPHRITIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005376'],
'DOID': ['DOID:10976'],
'UMLS': ['C0017665'],
'name': ['MEMBRANOUS GLOMERULONEPHRITIS'],
'MESH': ['D015433']})},
{'id': 'NAME:HYPERPLASIA',
'name': 'HYPERPLASIA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005043'],
'UMLS': ['C0020507'],
'name': ['HYPERPLASIA'],
'MESH': ['D006965']})},
{'id': 'NAME:HYPERTENSION',
'name': 'HYPERTENSION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005044'],
'DOID': ['DOID:10763'],
'UMLS': ['C0020538'],
'name': ['HYPERTENSION', 'HYPERTENSIVE DISEASE'],
'MESH': ['D006973']})},
{'id': 'NAME:RENAL HYPERTENSION',
'name': 'RENAL HYPERTENSION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0001105'],
'DOID': ['DOID:1073'],
'UMLS': ['C0020544'],
'name': ['RENAL HYPERTENSION'],
'MESH': ['D006977']})},
{'id': 'NAME:HYPERTROPHY',
'name': 'HYPERTROPHY',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0020564'],
'UMLS': ['C0020564'],
'name': ['HYPERTROPHY']})},
{'id': 'NAME:INFARCTION',
'name': 'INFARCTION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0021308'],
'UMLS': ['C0021308'],
'name': ['INFARCTION']})},
{'id': 'NAME:KIDNEY DISEASE',
'name': 'KIDNEY DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005240'],
'DOID': ['DOID:557'],
'UMLS': ['C0022658'],
'name': ['KIDNEY DISEASE', 'KIDNEY DISEASES'],
'MESH': ['D007674']})},
{'id': 'NAME:CHRONIC KIDNEY DISEASE',
'name': 'CHRONIC KIDNEY DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005300'],
'DOID': ['DOID:784'],
'UMLS': ['C1561643', 'C0022661'],
'name': ['CHRONIC KIDNEY DISEASE',
'CHRONIC KIDNEY DISEASES',
'KIDNEY FAILURE, CHRONIC'],
'MESH': ['D007676', 'D051436']})},
{'id': 'NAME:LUNG DISEASE',
'name': 'LUNG DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005275'],
'DOID': ['DOID:850'],
'UMLS': ['C0024115'],
'name': ['LUNG DISEASE', 'LUNG DISEASES'],
'MESH': ['D008171']})},
{'id': 'NAME:MYOCARDIAL INFARCTION',
'name': 'MYOCARDIAL INFARCTION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005068'],
'DOID': ['DOID:5844'],
'UMLS': ['C0027051'],
'name': ['MYOCARDIAL INFARCTION',
'MYOCARDIAL INFARCTION (DISEASE)'],
'MESH': ['D009203']})},
{'id': 'NAME:PROTEINURIA',
'name': 'PROTEINURIA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0003634'],
'DOID': ['DOID:576'],
'UMLS': ['C0033687'],
'name': ['PROTEINURIA'],
'MESH': ['D011507']})},
{'id': 'NAME:REPERFUSION INJURY',
'name': 'REPERFUSION INJURY',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0035126'],
'UMLS': ['C0035126'],
'name': ['REPERFUSION INJURY']})},
{'id': 'NAME:ACUTE RESPIRATORY DISTRESS SYNDROME',
'name': 'ACUTE RESPIRATORY DISTRESS SYNDROME',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0006502', 'MONDO:0001278'],
'DOID': ['DOID:11394'],
'UMLS': ['C0035222'],
'name': ['ACUTE RESPIRATORY DISTRESS SYNDROME',
'ADULT RESPIRATORY DISTRESS SYNDROME',
'RESPIRATORY DISTRESS SYNDROME, ADULT'],
'MESH': ['D012128']})},
{'id': 'NAME:CHAGAS DISEASE',
'name': 'CHAGAS DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0001444'],
'DOID': ['DOID:12140'],
'UMLS': ['C0041234'],
'name': ['CHAGAS DISEASE'],
'ORPHANET': ['3386']})},
{'id': 'NAME:ANEURYSM',
'name': 'ANEURYSM',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005385', 'MONDO:0019048'],
'UMLS': ['C0042373', 'C0002940', 'C0752130'],
'name': ['ANEURYSM',
'RARE VASCULAR DISEASE',
'SPINAL CORD ISCHEMIA',
'VASCULAR DISEASE',
'VASCULAR DISEASES'],
'ORPHANET': ['68362'],
'DOID': ['DOID:178'],
'MESH': ['D014652', 'D000783', 'D020758', 'D020760']})},
{'id': 'NAME:ESSENTIAL HYPERTENSION',
'name': 'ESSENTIAL HYPERTENSION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0001134'],
'DOID': ['DOID:10825'],
'UMLS': ['C0085580'],
'name': ['ESSENTIAL HYPERTENSION'],
'MESH': ['C562386']})},
{'id': 'NAME:FIBROSIS, LIVER',
'name': 'FIBROSIS, LIVER',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0239946'],
'UMLS': ['C0239946'],
'name': ['FIBROSIS, LIVER']})},
{'id': 'NAME:DYSLIPIDEMIAS',
'name': 'DYSLIPIDEMIAS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0015123'],
'UMLS': ['C0242339'],
'name': ['DYSLIPIDEMIAS', 'RARE DYSLIPIDEMIA'],
'ORPHANET': ['101953']})},
{'id': 'NAME:VENTRICULAR DYSFUNCTION',
'name': 'VENTRICULAR DYSFUNCTION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0242973'],
'UMLS': ['C0242973'],
'name': ['VENTRICULAR DYSFUNCTION']})},
{'id': 'NAME:KIDNEY ONCOCYTOMA',
'name': 'KIDNEY ONCOCYTOMA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0003825'],
'DOID': ['DOID:6245'],
'UMLS': ['C0346255'],
'name': ['KIDNEY ONCOCYTOMA', 'ONCOCYTOMA, RENAL'],
'MESH': ['C537750']})},
{'id': 'NAME:LEFT VENTRICULAR HYPERTROPHY',
'name': 'LEFT VENTRICULAR HYPERTROPHY',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0149721'],
'UMLS': ['C0149721'],
'name': ['LEFT VENTRICULAR HYPERTROPHY']})},
{'id': 'NAME:DIABETIC RETINOPATHY',
'name': 'DIABETIC RETINOPATHY',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005266'],
'DOID': ['DOID:8947'],
'UMLS': ['C0011884'],
'name': ['DIABETIC RETINOPATHY'],
'MESH': ['D003930']})},
{'id': 'NAME:HEART DISEASE',
'name': 'HEART DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005267'],
'DOID': ['DOID:114'],
'UMLS': ['C0018799'],
'name': ['HEART DISEASE', 'HEART DISEASES'],
'MESH': ['D006331']})},
{'id': 'NAME:IDIOPATHIC CARDIOMYOPATHY',
'name': 'IDIOPATHIC CARDIOMYOPATHY',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005110'],
'UMLS': ['C0033141'],
'name': ['IDIOPATHIC CARDIOMYOPATHY']})},
{'id': 'NAME:PELLAGRA',
'name': 'PELLAGRA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0019975'],
'DOID': ['DOID:8457'],
'UMLS': ['C0030783'],
'name': ['PELLAGRA'],
'MESH': ['D010383'],
'ORPHANET': ['97352']})},
{'id': 'NAME:HARTNUP DISEASE',
'name': 'HARTNUP DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0009324'],
'DOID': ['DOID:1060'],
'UMLS': ['C0018609'],
'name': ['HARTNUP DISEASE'],
'MESH': ['D006250'],
'OMIM': ['234500'],
'ORPHANET': ['2116']})},
{'id': 'NAME:ACUTE MYOCARDIAL INFARCTION',
'name': 'ACUTE MYOCARDIAL INFARCTION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0004781'],
'DOID': ['DOID:9408'],
'UMLS': ['C0155626'],
'name': ['ACUTE MYOCARDIAL INFARCTION']})},
{'id': 'NAME:NON-SMALL CELL LUNG CARCINOMA',
'name': 'NON-SMALL CELL LUNG CARCINOMA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005233'],
'DOID': ['DOID:3908'],
'UMLS': ['C0007131'],
'name': ['NON-SMALL CELL LUNG CARCINOMA',
'NON-SMALL CELL LUNG CARCINOMA (DISEASE)'],
'MESH': ['D002289']})},
{'id': 'NAME:CEREBROVASCULAR ACCIDENT',
'name': 'CEREBROVASCULAR ACCIDENT',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0011057'],
'DOID': ['DOID:6713'],
'UMLS': ['C0007820', 'C0038454', 'C0948008'],
'name': ['CEREBROVASCULAR ACCIDENT',
'CEREBROVASCULAR DISORDER',
'CEREBROVASCULAR DISORDERS',
'ISCHEMIC STROKE'],
'MESH': ['D020521', 'D002561'],
'OMIM': ['601367']})},
{'id': 'NAME:ADENOCARCINOMA OF LUNG (DISORDER)',
'name': 'ADENOCARCINOMA OF LUNG (DISORDER)',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005061'],
'DOID': ['DOID:3910'],
'UMLS': ['C1335060', 'C0152013'],
'name': ['ADENOCARCINOMA OF LUNG (DISORDER)',
'LUNG ADENOCARCINOMA'],
'MESH': ['C538231']})},
{'id': 'NAME:DYSEQUILIBRIUM SYNDROME',
'name': 'DYSEQUILIBRIUM SYNDROME',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0009133'],
'DOID': ['DOID:0050997'],
'UMLS': ['C0394006'],
'name': ['DYSEQUILIBRIUM SYNDROME'],
'MESH': ['C535731'],
'ORPHANET': ['1766']})},
{'id': 'NAME:CARDIOMYOPATHIES',
'name': 'CARDIOMYOPATHIES',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0004994'],
'DOID': ['DOID:0050700'],
'UMLS': ['C0878544', 'C0036529'],
'name': ['CARDIOMYOPATHIES', 'CARDIOMYOPATHY'],
'MESH': ['D009202'],
'ORPHANET': ['167848']})},
{'id': 'NAME:HEART FAILURE',
'name': 'HEART FAILURE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005252'],
'UMLS': ['C0018801'],
'name': ['HEART FAILURE'],
'MESH': ['D006333']})},
{'id': 'NAME:ACUTE RESPIRATORY FAILURE',
'name': 'ACUTE RESPIRATORY FAILURE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0021113'],
'DOID': ['DOID:11162'],
'UMLS': ['C1145670', 'C0264490'],
'name': ['ACUTE RESPIRATORY FAILURE', 'RESPIRATORY FAILURE'],
'MESH': ['D012131']})},
{'id': "NAME:ALZHEIMER'S DISEASE",
'name': "ALZHEIMER'S DISEASE",
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0004975'],
'DOID': ['DOID:10652'],
'UMLS': ['C0002395'],
'name': ["ALZHEIMER'S DISEASE", 'ALZHEIMERS DISEASE'],
'MESH': ['D000544']})},
{'id': 'NAME:PULMONARY HYPERTENSION',
'name': 'PULMONARY HYPERTENSION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005149'],
'DOID': ['DOID:6432'],
'UMLS': ['C0020542'],
'name': ['PULMONARY HYPERTENSION'],
'MESH': ['D006976']})},
{'id': 'NAME:DIABETES MELLITUS, NON-INSULIN-DEPENDENT',
'name': 'DIABETES MELLITUS, NON-INSULIN-DEPENDENT',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005148'],
'DOID': ['DOID:9352'],
'UMLS': ['C0011860'],
'name': ['DIABETES MELLITUS, NON-INSULIN-DEPENDENT',
'TYPE 2 DIABETES MELLITUS'],
'MESH': ['D003924']})},
{'id': 'NAME:METABOLIC DISEASE',
'name': 'METABOLIC DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005066'],
'DOID': ['DOID:0014667'],
'UMLS': ['C0025517'],
'name': ['METABOLIC DISEASE', 'METABOLIC DISEASES'],
'MESH': ['D008659']})},
{'id': 'NAME:CORONAVINAE INFECTIOUS DISEASE',
'name': 'CORONAVINAE INFECTIOUS DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005719'],
'name': ['CORONAVINAE INFECTIOUS DISEASE'],
'MESH': ['D018352']})},
{'id': 'NAME:PULMONARY EDEMA',
'name': 'PULMONARY EDEMA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0006932'],
'DOID': ['DOID:11396'],
'UMLS': ['C0034063'],
'name': ['PULMONARY EDEMA'],
'MESH': ['D011654']})},
{'id': 'NAME:CHRONIC RENAL FAILURE SYNDROME',
'name': 'CHRONIC RENAL FAILURE SYNDROME',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0024327'],
'UMLS': ['C0022661'],
'name': ['CHRONIC RENAL FAILURE SYNDROME',
'KIDNEY FAILURE, CHRONIC'],
'MESH': ['D051436']})},
{'id': 'NAME:SEVERE ACUTE RESPIRATORY SYNDROME',
'name': 'SEVERE ACUTE RESPIRATORY SYNDROME',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005091'],
'DOID': ['DOID:2945'],
'UMLS': ['C1175175'],
'name': ['SEVERE ACUTE RESPIRATORY SYNDROME'],
'MESH': ['D045169']})},
{'id': 'NAME:ARTERIOSCLEROSIS',
'name': 'ARTERIOSCLEROSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0002277'],
'DOID': ['DOID:2349'],
'UMLS': ['C0003850'],
'name': ['ARTERIOSCLEROSIS', 'ARTERIOSCLEROSIS (DISEASE)'],
'MESH': ['D001161']})},
{'id': 'NAME:RENAL AMINOACIDURIA',
'name': 'RENAL AMINOACIDURIA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0006944'],
'name': ['RENAL AMINOACIDURIA'],
'MESH': ['D000608']})},
{'id': 'NAME:PLEURAL TUBERCULOSIS',
'name': 'PLEURAL TUBERCULOSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005922'],
'DOID': ['DOID:106'],
'UMLS': ['C0041326'],
'name': ['PLEURAL TUBERCULOSIS'],
'MESH': ['D014396']})},
{'id': 'NAME:CORONARY ARTERIOSCLEROSIS',
'name': 'CORONARY ARTERIOSCLEROSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005010'],
'DOID': ['DOID:3393'],
'UMLS': ['C0151744',
'C0010054',
'C0264694',
'C0010068',
'C1956346'],
'name': ['CORONARY ARTERIOSCLEROSIS',
'CORONARY ARTERY DISEASE',
'CORONARY HEART DISEASE',
'MYOCARDIAL ISCHEMIA'],
'MESH': ['D003324', 'D017202', 'D003327']})},
{'id': 'NAME:INFERTILITY DUE TO EXTRATESTICULAR CAUSE',
'name': 'INFERTILITY DUE TO EXTRATESTICULAR CAUSE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0001877'],
'DOID': ['DOID:14096'],
'UMLS': ['C0021360'],
'name': ['INFERTILITY DUE TO EXTRATESTICULAR CAUSE']})},
{'id': 'NAME:CIRRHOSIS OF LIVER',
'name': 'CIRRHOSIS OF LIVER',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005155'],
'DOID': ['DOID:5082'],
'UMLS': ['C0023890'],
'name': ['CIRRHOSIS OF LIVER', 'LIVER CIRRHOSIS'],
'MESH': ['D008103']})},
{'id': 'NAME:SYSTOLIC HEART FAILURE',
'name': 'SYSTOLIC HEART FAILURE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0006993'],
'DOID': ['DOID:9651'],
'UMLS': ['C1135191'],
'name': ['SYSTOLIC HEART FAILURE'],
'MESH': ['D054143']})},
{'id': 'NAME:IDIOPATHIC PULMONARY HYPERTENSION',
'name': 'IDIOPATHIC PULMONARY HYPERTENSION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0015924'],
'UMLS': ['C2973725', 'C0152171'],
'name': ['IDIOPATHIC PULMONARY HYPERTENSION',
'PULMONARY ARTERIAL HYPERTENSION'],
'MESH': ['C536282'],
'ORPHANET': ['182090']})},
{'id': 'NAME:INFARCTION, MIDDLE CEREBRAL ARTERY',
'name': 'INFARCTION, MIDDLE CEREBRAL ARTERY',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0006857'],
'DOID': ['DOID:3525'],
'UMLS': ['C0740392'],
'name': ['INFARCTION, MIDDLE CEREBRAL ARTERY',
'MIDDLE CEREBRAL ARTERY INFARCTION'],
'MESH': ['D020244']})},
{'id': 'NAME:ATHEROSCLEROSIS',
'name': 'ATHEROSCLEROSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005311'],
'DOID': ['DOID:1936'],
'UMLS': ['C0004153'],
'name': ['ATHEROSCLEROSIS'],
'MESH': ['D050197']})},
{'id': 'NAME:ABDOMINAL AORTIC ANEURYSM',
'name': 'ABDOMINAL AORTIC ANEURYSM',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005350'],
'DOID': ['DOID:7693'],
'UMLS': ['C0162871'],
'name': ['ABDOMINAL AORTIC ANEURYSM',
'AORTIC ANEURYSM, ABDOMINAL'],
'MESH': ['D017544']})},
{'id': 'NAME:ENDOMYOCARDIAL FIBROSIS',
'name': 'ENDOMYOCARDIAL FIBROSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0006746'],
'DOID': ['DOID:12932'],
'UMLS': ['C0553980'],
'name': ['ENDOMYOCARDIAL FIBROSIS'],
'MESH': ['D004719']})},
{'id': 'NAME:GLAUCOMA',
'name': 'GLAUCOMA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005041'],
'DOID': ['DOID:1686'],
'UMLS': ['C0017601'],
'name': ['GLAUCOMA', 'GLAUCOMA (DISEASE)'],
'MESH': ['D005901']})},
{'id': 'NAME:BILIARY CIRRHOSIS',
'name': 'BILIARY CIRRHOSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005388'],
'DOID': ['DOID:12236'],
'UMLS': ['C0023892', 'C0008312', 'C0859942'],
'name': ['BILIARY CIRRHOSIS',
"HANOT'S CIRRHOSIS",
'PRIMARY BILIARY CHOLANGITIS',
'PRIMARY BILIARY CIRRHOSIS'],
'MESH': ['D008105'],
'ORPHANET': ['186']})},
{'id': 'NAME:NICOTINE DEPENDENCE',
'name': 'NICOTINE DEPENDENCE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0008575'],
'DOID': ['DOID:0050742'],
'UMLS': ['C1861063', 'C0028043'],
'name': ['NICOTINE DEPENDENCE',
'TOBACCO ADDICTION, SUSCEPTIBILITY TO (FINDING)'],
'MESH': ['D012907', 'D014029'],
'OMIM': ['188890']})},
{'id': 'NAME:SPONTANEOUS ABORTION',
'name': 'SPONTANEOUS ABORTION',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['C0000786'],
'UMLS': ['C0000786'],
'name': ['SPONTANEOUS ABORTION']})},
{'id': 'NAME:INJURY',
'name': 'INJURY',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0021178'],
'UMLS': ['C3263723'],
'name': ['INJURY']})},
{'id': 'NAME:HYPOTENSION (DISEASE)',
'name': 'HYPOTENSION (DISEASE)',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005468'],
'name': ['HYPOTENSION (DISEASE)'],
'MESH': ['D007022']})},
{'id': 'NAME:MECONIUM ASPIRATION SYNDROME',
'name': 'MECONIUM ASPIRATION SYNDROME',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0006851'],
'DOID': ['DOID:11049'],
'UMLS': ['C0025048'],
'name': ['MECONIUM ASPIRATION SYNDROME'],
'MESH': ['D008471'],
'ORPHANET': ['70588']})},
{'id': 'NAME:MCCUNE-ALBRIGHT SYNDROME',
'name': 'MCCUNE-ALBRIGHT SYNDROME',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0018919'],
'UMLS': ['C0242292'],
'name': ['MCCUNE-ALBRIGHT SYNDROME'],
'MESH': ['D005359'],
'ORPHANET': ['562']})},
{'id': 'NAME:LYMPHOPENIA',
'name': 'LYMPHOPENIA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0003783'],
'DOID': ['DOID:614'],
'UMLS': ['C0024312'],
'name': ['LYMPHOPENIA', 'LYMPHOPENIA (DISEASE)'],
'MESH': ['D008231']})},
{'id': 'NAME:MACROPHAGE ACTIVATION SYNDROME',
'name': 'MACROPHAGE ACTIVATION SYNDROME',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0015545'],
'UMLS': ['C1096155'],
'name': ['MACROPHAGE ACTIVATION SYNDROME'],
'MESH': ['D055501'],
'ORPHANET': ['158061']})},
{'id': 'NAME:NEURAL TUBE DEFECT',
'name': 'NEURAL TUBE DEFECT',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0018075'],
'DOID': ['DOID:0080074'],
'UMLS': ['C0027794'],
'name': ['NEURAL TUBE DEFECT', 'NEURAL TUBE DEFECTS'],
'MESH': ['D009436'],
'ORPHANET': ['3388']})},
{'id': 'NAME:RETINITIS PIGMENTOSA 3',
'name': 'RETINITIS PIGMENTOSA 3',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0010227'],
'DOID': ['DOID:0110414'],
'UMLS': ['C1845667'],
'name': ['RETINITIS PIGMENTOSA 3'],
'MESH': ['C564520'],
'OMIM': ['300029']})},
{'id': 'NAME:URINARY SYSTEM DISEASE',
'name': 'URINARY SYSTEM DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0002118'],
'DOID': ['DOID:18'],
'UMLS': ['C1335051'],
'name': ['URINARY SYSTEM DISEASE'],
'MESH': ['D014570']})},
{'id': 'NAME:CONGENITAL NONBULLOUS ICHTHYOSIFORM ERYTHRODERMA',
'name': 'CONGENITAL NONBULLOUS ICHTHYOSIFORM ERYTHRODERMA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0017778'],
'UMLS': ['C0079154'],
'name': ['CONGENITAL NONBULLOUS ICHTHYOSIFORM ERYTHRODERMA',
'LAMELLAR ICHTHYOSIS'],
'MESH': ['D017490'],
'ORPHANET': ['313']})},
{'id': 'NAME:SYNDROMIC DISEASE',
'name': 'SYNDROMIC DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0002254'],
'DOID': ['DOID:225'],
'UMLS': ['C0039082'],
'name': ['SYNDROMIC DISEASE'],
'MESH': ['D013577']})},
{'id': 'NAME:KIDNEY FAILURE',
'name': 'KIDNEY FAILURE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0001106'],
'DOID': ['DOID:1074'],
'UMLS': ['C0035078'],
'name': ['KIDNEY FAILURE'],
'MESH': ['D051437']})},
{'id': 'NAME:IMPAIRED RENAL FUNCTION DISEASE',
'name': 'IMPAIRED RENAL FUNCTION DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0001343'],
'DOID': ['DOID:11705'],
'UMLS': ['C0029791'],
'name': ['IMPAIRED RENAL FUNCTION DISEASE']})},
{'id': 'NAME:ACUTE KIDNEY FAILURE',
'name': 'ACUTE KIDNEY FAILURE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0002492'],
'DOID': ['DOID:3021'],
'name': ['ACUTE KIDNEY FAILURE'],
'MESH': ['D058186']})},
{'id': 'NAME:PNEUMONIA',
'name': 'PNEUMONIA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005249'],
'DOID': ['DOID:552'],
'UMLS': ['C0032285'],
'name': ['PNEUMONIA'],
'MESH': ['D011014']})},
{'id': 'NAME:FOCAL GLOMERULOSCLEROSIS',
'name': 'FOCAL GLOMERULOSCLEROSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005363'],
'DOID': ['DOID:1312'],
'UMLS': ['C0017668'],
'name': ['FOCAL GLOMERULOSCLEROSIS',
'FOCAL SEGMENTAL GLOMERULOSCLEROSIS'],
'MESH': ['D005923']})},
{'id': 'NAME:LIVER DISEASE',
'name': 'LIVER DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005154'],
'DOID': ['DOID:409'],
'UMLS': ['C0023895'],
'name': ['LIVER DISEASE', 'LIVER DISEASES'],
'MESH': ['D008107']})},
{'id': 'NAME:KIDNEY CANCER',
'name': 'KIDNEY CANCER',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0002367'],
'DOID': ['DOID:263'],
'UMLS': ['C0740457', 'C0022665', 'C0494158'],
'name': ['KIDNEY CANCER',
'KIDNEY NEOPLASM',
'MALIGNANT NEOPLASM OF KIDNEY'],
'MESH': ['D007680']})},
{'id': 'NAME:CHOLERA',
'name': 'CHOLERA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0015766'],
'DOID': ['DOID:1498'],
'UMLS': ['C0008354'],
'name': ['CHOLERA'],
'MESH': ['D002771'],
'ORPHANET': ['173']})},
{'id': 'NAME:MALARIA',
'name': 'MALARIA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005136'],
'DOID': ['DOID:12365'],
'UMLS': ['C1969379',
'C1970029',
'C1970028',
'C0024530',
'C2720293',
'C1855457'],
'name': ['MALARIA',
'MALARIA, CEREBRAL, RESISTANCE TO',
'MALARIA, CEREBRAL, SUSCEPTIBILITY TO (FINDING)',
'MALARIA, RESISTANCE TO',
'MALARIA, SEVERE, SUSCEPTIBILITY TO',
'MALARIA, SUSCEPTIBILITY TO (FINDING)'],
'MESH': ['D008288'],
'ORPHANET': ['673']})},
{'id': 'NAME:INTERSTITIAL LUNG DISEASE',
'name': 'INTERSTITIAL LUNG DISEASE',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0015925'],
'DOID': ['DOID:3082'],
'UMLS': ['C0206062'],
'name': ['INTERSTITIAL LUNG DISEASE',
'LUNG DISEASES, INTERSTITIAL'],
'MESH': ['D017563'],
'ORPHANET': ['182095']})},
{'id': 'NAME:INFLUENZA',
'name': 'INFLUENZA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005812'],
'DOID': ['DOID:8469'],
'UMLS': ['C0021400'],
'name': ['INFLUENZA'],
'MESH': ['D007251']})},
{'id': 'NAME:DEGENERATIVE DISORDER',
'name': 'DEGENERATIVE DISORDER',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005559'],
'DOID': ['DOID:1289'],
'UMLS': ['C0524851', 'C1285162'],
'name': ['DEGENERATIVE DISORDER',
'NEURODEGENERATIVE DISEASE',
'NEURODEGENERATIVE DISORDERS'],
'MESH': ['D019636']})},
{'id': 'NAME:URETERAL OBSTRUCTION (DISEASE)',
'name': 'URETERAL OBSTRUCTION (DISEASE)',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0003329'],
'DOID': ['DOID:5199'],
'UMLS': ['C0029866'],
'name': ['URETERAL OBSTRUCTION (DISEASE)'],
'MESH': ['D014517']})},
{'id': 'NAME:OBESITY',
'name': 'OBESITY',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0011122'],
'DOID': ['DOID:9970'],
'UMLS': ['C0028754', 'C0039870'],
'name': ['OBESITY', 'OBESITY (DISEASE)', 'THINNESS'],
'MESH': ['D009765'],
'OMIM': ['601665']})},
{'id': 'NAME:THROMBOSIS',
'name': 'THROMBOSIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0000831'],
'DOID': ['DOID:0060903'],
'UMLS': ['C0040053'],
'name': ['THROMBOSIS', 'THROMBOTIC DISEASE'],
'MESH': ['D013927']})},
{'id': 'NAME:TRYPANOSOMIASIS',
'name': 'TRYPANOSOMIASIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0000940'],
'DOID': ['DOID:10113'],
'UMLS': ['C0041227'],
'name': ['TRYPANOSOMIASIS'],
'MESH': ['D014352']})},
{'id': 'NAME:DIARRHEA (DISEASE)',
'name': 'DIARRHEA (DISEASE)',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0001673'],
'DOID': ['DOID:13250'],
'UMLS': ['C0013369'],
'name': ['DIARRHEA (DISEASE)'],
'MESH': ['D003967']})},
{'id': 'NAME:INHERITED LIPID METABOLISM DISORDER',
'name': 'INHERITED LIPID METABOLISM DISORDER',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0002525'],
'DOID': ['DOID:3146'],
'UMLS': ['C0154251', 'C0023772'],
'name': ['INHERITED LIPID METABOLISM DISORDER',
'LIPID METABOLISM DISORDERS',
'LIPID METABOLISM, INBORN ERRORS'],
'MESH': ['D008052'],
'ORPHANET': ['309005']})},
{'id': 'NAME:CARCINOMA',
'name': 'CARCINOMA',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0004993'],
'DOID': ['DOID:305'],
'UMLS': ['C0553707', 'C1368683'],
'name': ['CARCINOMA', 'EPITHELIOMA'],
'MESH': ['D002277', 'D009375']})},
{'id': 'NAME:TETANUS',
'name': 'TETANUS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0005526'],
'DOID': ['DOID:11338'],
'UMLS': ['C0039614'],
'name': ['TETANUS'],
'MESH': ['D013742'],
'ORPHANET': ['3299']})},
{'id': 'NAME:GINGIVITIS',
'name': 'GINGIVITIS',
'type': 'Disease',
'equivalent_identifiers': defaultdict(set,
{'MONDO': ['MONDO:0002508'],
'DOID': ['DOID:3087'],
'UMLS': ['C0017574', 'C0155937'],
'name': ['GINGIVITIS'],
'MESH': ['D005891']})}],
'edges': [{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0221198',
'edge_source': 'SEMMED Gene API',
'id': 'fe1de0617fe7846690b517bad50e5bc76ae07a95c7fb5c1851c9e044788cb832',
'type': 'disrupts'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0221198',
'edge_source': 'SEMMED Gene API',
'id': '9fb944d2110cb8fc40723f3bb3823d39b66ee796a41d7c38cc1c26c4fd6b5549',
'type': 'causes'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0262613',
'edge_source': 'SEMMED Gene API',
'id': 'c79ac791db0188bb5911eecbf5ea97a31db177360e7fbb966b64a941f7e1db19',
'type': 'disrupts'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0264716',
'edge_source': 'SEMMED Gene API',
'id': '3abd5ff89a65a1ad07d4888a383c7f35ea014091fef867dfacf9e9da00ad35b0',
'type': 'disrupts'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0264716',
'edge_source': 'SEMMED Gene API',
'id': '383b337666e5220fd7f1a9907ca28427f89239fcacdaea8cbb8d7c3adb1ab991',
'type': 'related_to'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C1397014',
'edge_source': 'SEMMED Gene API',
'id': '177cd061184980cc658a0e455a21cdaf3331229cbf2bc99f9588f1ef29db0adb',
'type': 'disrupts'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0009566',
'edge_source': 'SEMMED Gene API',
'id': '08a4a2203d83428f03324ba36af376e12a959afefcaa1a46df2aeb2be3dc60e7',
'type': 'causes'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0011847',
'edge_source': 'SEMMED Gene API',
'id': '90cee976e37dcdc353cf0eb0785fdb19b50743cca4017cdd1149dadefd36e263',
'type': 'causes'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0011847',
'edge_source': 'SEMMED Gene API',
'id': '32f9b96316b37edacf74d2f7d3b2e31827bc7544edbcccc366f3c7c5c3d0f197',
'type': 'related_to'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0015697',
'edge_source': 'SEMMED Gene API',
'id': 'af995901735943ef66cda769a88654efc0d9d60af54260d1a51338402d6a56c4',
'type': 'causes'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0015697',
'edge_source': 'SEMMED Gene API',
'id': '6c11d1bed64d243db281944bb72981bd53fb79fa7c2457aa8429b03fd1b513a9',
'type': 'treats'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0242606',
'edge_source': 'SEMMED Gene API',
'id': '51243372420f35b016101e7f4f029d41b7e74c2fb882ba701f468d1401a1ebba',
'type': 'causes'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0242606',
'edge_source': 'SEMMED Gene API',
'id': '6f66805c379b6213758e0a9b7a96f3250a11789750e08b32a2f9d5a0acce9842',
'type': 'related_to'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0332448',
'edge_source': 'SEMMED Gene API',
'id': '0bb56600780dc8d067fb3eddf10c004afd16a95e04aba0bc17e3492738c1d74f',
'type': 'causes'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0340515',
'edge_source': 'SEMMED Gene API',
'id': 'c3d31b2fc0a39103ef750e7eab203d7553b52945ac994d16d7829afead36b2a7',
'type': 'causes'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0340515',
'edge_source': 'SEMMED Gene API',
'id': 'dc86d4435e81fad154b91cceb60eebca450e23ca22a668a5503e8b8cd3e37fcb',
'type': 'related_to'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0522569',
'edge_source': 'SEMMED Gene API',
'id': 'ea3002a552c221b62ee4c34eee689056d4a191d18472b3a5323ce2c80fba6b93',
'type': 'causes'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C1291117',
'edge_source': 'SEMMED Gene API',
'id': '6e288ef801633bbb2bc98e2a8b1437f6d95194e8bd33ff53b8edf39a9f10791a',
'type': 'causes'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0277785',
'edge_source': 'SEMMED Gene API',
'id': '529efbade918824abe7259ca856d51f99324ff6111aefb410760cd82c45d3766',
'type': 'prevents'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0277785',
'edge_source': 'SEMMED Gene API',
'id': 'f691113146b377fd307d6bbdde7e0e50a28b4360d9669493e6b8f1b14ed217c4',
'type': 'related_to'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0277785',
'edge_source': 'SEMMED Gene API',
'id': 'f691113146b377fd307d6bbdde7e0e50a28b4360d9669493e6b8f1b14ed217c4',
'type': 'related_to'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0699748',
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'id': 'ae6136e6735bba2c005082cce4b64838a0ab8e50589179b1cf294a6d87034bf1',
'type': 'prevents'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C1155266',
'edge_source': 'SEMMED Gene API',
'id': 'ab93b3517a476222410b0b44a57d55eb767c136014f59c69e6a756436097accf',
'type': 'prevents'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0231176',
'edge_source': 'SEMMED Gene API',
'id': 'afc6975b1274a5b043403488d66e7237d99939b94caff7857b183cefdbeef9ed',
'type': 'treats'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C1301752',
'edge_source': 'SEMMED Gene API',
'id': 'fcc4025030afbb96594ffeb2e33cc3dedbb580bcf569f49b545cc9436616d76e',
'type': 'treats'},
{'source_id': 'SYMBOL:ACE2',
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'edge_source': 'SEMMED Gene API',
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'type': 'related_to'},
{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
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'id': '7c0c8f6a7115c2dd6d5dbd53a99e06a5923afeb8ad61ff2facbca670b8937579',
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{'source_id': 'SYMBOL:ACE2',
'target_id': 'UMLS:C0878751',
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{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
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{'source_id': 'SYMBOL:ACE2',
'target_id': 'MONDO:MONDO:0100096',
'edge_source': 'Automat CORD19 Scigraph API',
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'type': 'related_to'},
{'source_id': 'SYMBOL:ACE2',
'target_id': 'MESH:D000022',
'edge_source': 'CTD API',
'id': 'fa8975bdf6388ed764a04f7dbd15570b667b189596ab99a36a4f7068418c9565',
'type': 'related_to'},
{'source_id': 'SYMBOL:ACE2',
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Content source: biothings/biothings_explorer
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